Research use only. Drug rankings reflect computational scoring against 75+ databases and AlphaFold structural data. High confidence tiers indicate strong pathway-target alignment — not clinical efficacy. All outputs require expert validation before any clinical application.
① Ranked Drug Candidates Precision@10 = 100% ⓘ (n=22) · accuracy data →
② Enriched Pathways
③ Therapeutic Strategies
④ Novel Hypotheses
⑤ TCGA Survival Stratification
Source: cBioPortal · TCGA cohort · OS = overall survival · HR = hazard ratio (mutated vs wildtype)
📅 Evidence Timeline
Publication density of cited papers by year — see if evidence is accelerating or stagnant
🔥 Gene Interaction Heatmap
Interaction scores between input genes (STRING/BioGRID data)
Cell color = interaction score (dark teal = strong, white = none). Source: STRING + BioGRID
⚗️ Combination Hypotheses
Top synergistic pairs scored by MOA complementarity, pathway coverage, and clinical precedent
Synergy Experiment Protocol
Bliss · ZIP · Checkerboard Design
Clinical Report
Print-ready · Tumor Board · PDF
Generate a structured clinical-grade HTML report covering drug candidates, biomarkers, survival data, and resistance forecasts. Open in a new tab and use browser Print → Save as PDF.
Research Brief Generator
AI-generated · 4 formats
Generating brief with AI…
New Preprints Matching This Analysis
No new preprints yet. GaiaLab monitors bioRxiv and medRxiv daily for papers matching your gene panel.