Chronology is a scientific variable

Evidence After Lock

GaiaLab separates what was knowable at prediction time from observations that became public later. A later trial registration can establish temporal research-direction correspondence; it does not by itself prove efficacy, mechanism, or clinical validity.

Before lock

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Prediction records in the public ledger. Their recorded timestamps define the comparison point used below.

After lock

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Records where a matched trial's first-posted date is strictly later than GaiaLab's prediction timestamp, when both timestamps are available.

Later observations

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Interpretation boundary

This page performs a chronology split over available public ledger fields. It does not relabel retrospective studies, substitute for a preregistered outcome rule, or certify that a later paper/trial was independent of all pre-lock information. Fully governed prospective studies remain in the Prospective Registry.