Live Trust Scoreboard
How to Read These Signals
Trust signals update after each analysis run. Use Evidence Density and Citation Coverage to gauge data richness. Monitor the Contradiction Index to identify areas requiring manual review. The Quality Score provides a single composite measure for triage decisions.
Platform Integrity Snapshot
Live operational metrics from the additive Postgres analytics spine. This complements the browser-local latest run with cross-run export quality, workspace collaboration, and platform activity signals.
Latest Run Detail
Detailed breakdown of the most recent analysis. Data is stored locally in this browser session.
Pipeline Overview
A six-stage pipeline that keeps evidence provenance, scoring, and replayability transparent at every step.
Evidence Ledger Format
Each claim is tracked with source identifiers, confidence tier, and constraint notes.
| Claim | Evidence IDs | Confidence | Notes |
|---|---|---|---|
| EGFR is implicated in NSCLC | PMID:123456; OpenTargets:OTAR1234 | High | Strong agreement across sources |
| KRAS drives MAPK activation | PMID:987654; KEGG:hsa04010 | High | Consensus across pathway databases |
Confidence Scoring Policy
Confidence is consensus-weighted across independent sources. The formula applies diminishing returns, contradiction penalties, and a hard cap at 0.95 to prevent false certainty.
Scoring formula
contradiction_penalty = 0.25 * CI
final = clamp(base + bonus - penalty, 0, 0.95)
A = number of independent source domains in agreement
CI = contradiction index for this claim
Contradiction Handling
When sources disagree, GaiaLab does not average away conflict. Contradictions are surfaced with supporting and refuting evidence for manual adjudication.
Severity: Medium
Support: PMID:112233
Refute: PMID:445566
Reproducible Snapshots
Every analysis produces a replayable snapshot containing inputs, source versions, scoring policy, model configuration, evidence ledger, and visualization state.
Snapshots are also accessible at /analysis/{id} after each run. The analysis ID appears in every API response under analysisId.
Prediction Calibration
GaiaLab prospectively records drug repurposing predictions and checks them against ClinicalTrials.gov outcomes. A well-calibrated system's 80% confidence predictions should be correct ~80% of the time.
Research Direction Rate (RDR) measures whether the research community independently investigated the same therapeutic direction — a concordance signal, not a proof of efficacy. AUROC 0.545 is marginally above the 0.50 random baseline; this is a modest but statistically non-trivial signal on an unsupervised task with no disease-specific tuning. These metrics are self-reported against public datasets; third-party replication has not been performed. Precision@10 figures cited elsewhere reflect performance on a small internal benchmark set and should not be generalised. Completed trial status in the concordance ledger means the trial finished enrollment — it does not indicate that the drug was found efficacious. All outputs are research hypotheses requiring independent experimental validation.
Safety & Scope
- Research and exploratory use only.
- No dosing recommendations or clinical decision support.
- No patient-specific diagnostic or treatment advice.
- Low-evidence findings are labeled as hypotheses with suggested validation paths.