Omics Integration

RNA-seq Analysis

Upload DESeq2, edgeR, or limma results. GaiaLab extracts your significant genes and runs the full biomedical intelligence pipeline β€” pathways, drugs, hypotheses, and survival β€” automatically.

DESeq2 .csv edgeR .tsv limma .txt .rnk Seurat avg_log2FC

Upload expression results

Accepts any CSV/TSV with gene symbols, log2 fold-change, and adjusted p-value columns. Column names are detected automatically.

πŸ“‚
Drop your file here or click to browse
.csv Β· .tsv Β· .txt Β· .rnk β€” max 50 MB

Research use only. Not for diagnosis, treatment selection, or clinical decision-making. Upload only differential-expression tables (gene, log2FoldChange, padj). Do not upload protected health information (PHI) or identifiable patient records.

What GaiaLab does with your file ⬇ Download example DESeq2 CSV
  1. 1Extracts significant DE genes using your thresholds below (default: |logβ‚‚FC| β‰₯ 1.0, padj ≀ 0.05)
  2. 2Runs the full analysis pipeline on those genes β€” identical to submitting them on the homepage
  3. 3Returns: ranked drug candidates, KEGG/Reactome pathway enrichment, mechanistic hypotheses, evidence ledger (76+ databases), and ClinicalTrials.gov concordance for your DE signature
Typical yield: a DESeq2 result with 20,000 genes at default thresholds yields 200–500 significant DE genes; GaiaLab takes the top 50 by |logβ‚‚FC| for the pipeline.

Significant genes

Genelogβ‚‚FCpadjDirection
Submitting genes to GaiaLab…
This takes 30–60 seconds on first run.

How it works

1
Upload results
Drop any DESeq2, edgeR, or limma output. Column names are detected automatically.
2
Filter DEGs
Set your logFC and padj thresholds. Preview the significant gene list before submitting.
3
Full analysis
GaiaLab queries 76+ biological databases β€” pathways, drugs, hypotheses, survival β€” on your DEG list.
4
RNA-seq overlay
Results include your expression direction context β€” upregulated vs. downregulated gene annotations.

Expected column names (auto-detected)

Gene symbol
gene Β· gene_name Β· gene_symbol Β· Hugo_Symbol Β· hgnc_symbol Β· external_gene_name
Logβ‚‚ fold-change
log2FoldChange Β· logFC Β· avg_log2FC Β· log2fc Β· LFC
Adjusted p-value
padj Β· adj.P.Val Β· FDR Β· q_value Β· p.adjust Β· BH